The answer to this very popular question, “Are Maltipoos Hypoallergenic?” is not a simple one. Yes, the Maltipoo breed does have hair instead of fur, which most people think is the reason for being hypoallergenic. But most people that have allergies are allergic to the dander (dead skin cells that fall off and collect in the fur) and not the coat of the dog. Both dogs with fur and dogs with hair have dander. The top layer of skin is in a constant state of renewal where the dead cells are replaced with new ones, just like humans.
The thing that makes the difference in the severity of the allergic response is that fur is usually a lot thicker than hair. Because fur is thicker, it holds onto and collects the dander. The Maltipoo hair is silky and soft, which allows the dander to fall out. When a person that suffers from allergies pets or grooms a dog, they come into contact with whatever is on the coat. With the Maltipoo, there is much less dander that has collected so a person may have a smaller allergic response when handling the dog.
Also, Maltipoos are said to be non-shedding, but this is not entirely true. The coat will shed any dead hairs and replace with new ones just like the skin. This happens at a much slower rate than dogs with fur so there will be less dead hairs around the house to cause allergic reactions.
To conclude, the Maltipoo or any other breed with hair is not 100% hypoallergenic. They should be considered low-allergenic.
When someone with allergies is considering purchasing a Maltipoo, it is recommended to hold the dog/puppy for at least 20 minutes to see if it causes any kind of reaction. Be sure to do this indoors since the air outside can push the dander away and give false results.